What is the Entourage Effect?

Cannabinoids exert their effects by binding to specific receptors in our body. Within our endocannabinoid system, there are two main receptors known as CB1 and CB2. The CB1 receptor, primarily located in the brain, mediates various responses. When activated by THC, it produces a psychotropic high. On the other hand, CBD binding to CB1 receptors may result in reduced stress and anxiety, as well as potential pain and inflammation relief. CBD can also potentially mitigate the psychotropic effects of THC and alleviate stress and anxiety. It aids in promoting homeostasis, which is crucial for optimal balance and functioning in our bodies. Further research is needed to fully understand the comprehensive effects of CBD. CBD is considered “poly-pharmacological,” meaning it can affect multiple parts of the body simultaneously. Therefore, it is essential to comprehend the interactions and changes it induces in the user’s body. Scientists are actively conducting clinical research to uncover the complete range of CBD’s effects. To achieve the entourage effect, it is crucial to retain all the naturally occurring components of the cannabis plant, including cannabinoids, terpenes, flavonoids, and fatty acids, during the extraction and manufacturing processes of full-spectrum CBD products. If any of these components are missing from the final product, the entourage effect cannot be achieved, indicating that it is not a true full-spectrum product. The entourage effect stems from the synergistic relationship among all the naturally occurring cannabinoids present in the hemp plant. Put simply, it is the result of cannabinoids working together harmoniously to produce the effects intended by nature. The interaction of the plant’s natural components within our bodies yields a more potent influence compared to using a single cannabinoid in isolation. This phenomenon is known as the Entourage Effect.